Pingya Li

author: Time:2022-01-29 Number of hits:

Name

Pingya Li

Title

Professor

Address

Room 124, School of Basic Medical

Tel.

0431-85619803

Email

lipy@jlu.edu.cn

Education Background

1978-1983 Bachelor, Chemistry, Sichuan University

1983-1985 Master, School of Basic Medical Sciences, Norman Bethune Medical University

1994-1999 Ph.D., Traditional Chinese Medicine, Shenyang Pharmaceutical University

Work Experience

2000- Professor & doctoral supervisor, School of Pharmacitical Science, Jilin University

2015- Director, National and Local Joint Engineering Research Center for Ginseng Innovative Drug Development in Jilin Province

2017- Director, Natural Medicine Research Center of Jilin University

1999-2000 Professor, School of Basic Medical Sciences, Norman Bethune Medical University

1988-1994 Vice Professor & master supervisor, School of Basic Medical Sciences, Norman Bethune Medical University

1983-1985 Assistant Professor, School of Basic Medical Sciences, Norman Bethune Medical University

Courses


Research Field

Chemical constituents and biological activities of natural medicines; Structural modifications; Quality control; New drug Invention

Scientific Research Achievements

Publications:

Journals:

1. WANG, C. Z., YUAN, Y. Z., PAN, H., HSU, A. C. Y., CHEN, J. L., LIU, J. P.,LI, P. Y.& WANG, F.*2020. Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics.International Journal of Molecular Sciences,21,2577.

2. FU, T. H., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& GAO, Y. G. 2020. alpha-Mangostin exhibits antidepressant-like effects mediated by the modification of GABAergic, serotonergic and dopaminergic systems.Natural Product Research,34,868-871.

3. TAN, J., LIU, J. L., WANG, H., ZHANG, Y., LIN, H. Q., WANG, N. Y., SI, H. R., ZHANG, Y. T., LIU, J. P.*,LI, P. Y.*& SUN, K.*2020. Identification of blood-activating components from Xueshuan Xinmaining Tablet based on the spectrum-effect relationship and network pharmacology analysis.Rsc Advances,10, 9587-9600.

4. YANG, N., WANG, H., LIN, O. Q., LIU, J. L., ZHOU, B. S., CHEN, X. L., WANG, C. Z., LIU, J. P.*&LI, P. Y.*2020. Comprehensive metabolomics analysis based on UPLC-Q/TOF-MSE and the anti-COPD effect of different parts ofCelastrus orbiculatus Thunb.Rsc Advances,10,8396-8420.

5. WANG, C. Z., DONG, Q. H., WU, F. L., LI, Z.,LI, P. Y., LIU, J. P. & WANG, F.*2020. A new alkynol compound fromPlatycodins foliumand its cytotoxicity.Natural Product Research,7.

6. ZHENG, Q., WANG, R. L., ZHANG, N. Q., WANG, C. Z. &LI, P. Y.*2020. In vivo pharmacokinetics, distribution, and excretion of an anticancer agent isolated from red ginseng, in rat.Xenobiotica,50, 1323-1331.

7. QI, Z., WANG, Z., ZHOU, B., FU, S., HONG, T.,LI, P. Y.*& LIU, J. P.*2020. A new ocotillol-type ginsenoside from stems and leaves ofPanax quinquefoliumL. and its anti-oxidative effect on hydrogen peroxide exposed A549 cells.Natural Product Research,34, 2474-2481.

8. LIN, H. Q., ZHU, H. L., TAN, J., WANG, H., WANG, Z. Y.,LI, P. Y.*, ZHAO, C. F.*& LIU, J. P.*2019. Comparative Analysis of Chemical Constituents ofMoringa oleiferaLeaves from China and India by Ultra-Performance Liquid Chromatography Coupled with Quadrupole-Time-Of-Flight Mass Spectrometry.Molecules,24,25.

9. LIN, H. Q., ZHU, H. L., TAN, J., WANG, H., DONG, Q. G., WU, F. L., LIU, Y. H.,LI, P. Y.*& LIU, J. P.*2019. Non-Targeted Metabolomic Analysis of Methanolic Extracts of Wild-Simulated and Field-Grown American Ginseng.Molecules,24,25.

10. QI, Z., LI, Z., GUAN, X. W., WANG, C. Z., WANG, F.,LI, P. Y.*& LIU, J. P.*2019. Four Novel Dammarane-Type Triterpenoids from Pearl Knots ofPanax ginseng Meyer cv. Silvatica.Molecules,24,13.

11. WANG, C. Z., LIN, H. Q., YANG, N., WANG, H., ZHAO, Y.,LI, P. Y., LIU, J. P.*& WANG, F.* 2019. Effects ofPlatycodins Foliumon Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics.Molecules,24, 20.

12. LIN, H. Q., ZHU, H. L., TAN, J., WANG, C. Z., DONG, Q. H., WU, F. L., WANG, H., LIU, J. L.,LI, P. Y.*& LIU, J. P.* 2019. Comprehensive Investigation on Metabolites of Wild-Simulated American Ginseng Root Based on Ultra-High-Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry.Journal of agricultural and food chemistry,67,5801-5819.

13. QI, Z., LI, W., TAN, J., WANG, C. Z., LIN, H. Q., ZHOU, B. S., LIU, J. P. &LI, P. Y.*2019. Effect of ginsenoside Rh2 on renal apoptosis in cisplatin-induced nephrotoxicity in vivo.Phytomedicine, 61,14.

14. ZHANG, K., LIU, Y., WANG, C. Z., LI, J. N., XIONG, L. X., WANG, Z. Z., LIU, J. P.*&LI, P. Y.*2019. Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice.Journal of Ginseng Research,43,550-561.

15. WU, D., WANG, H., TAN, J., WANG, C., LIN, H., ZHU, H., LIU, J. P.,LI, P. Y.& YIN, J. Y.*2019. Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS.Molecules,24.

16. ZHU, H. L., LIU, J. L., LIN, H. Q., ZHANG, Y., YANG, N., ZHOU, B. S., WANG, Z. Y., HSU, A. C. Y., LIU, J. P.*&LI, P. Y.*2019. UPLC-QTOF-MS-guided isolation of anti-COPD ginsenosides from wild ginseng.Rsc Advances,9, 38658-38668.

17. QI, Z., CHEN, L. X., LI, Z., SHAO, Z. J., QI, Y. L., GAO, K., LIU, S. X., SUN, Y. S.*,LI, P. Y. & LIU, J. P.*2019. Immunomodulatory Effects of (24R)-Pseudo-Ginsenoside HQ and (24S)-Pseudo-Ginsenoside HQ on Cyclophosphamide-Induced Immunosuppression and Their Anti-Tumor Effects Study.International journal of molecular sciences,20,836.

18. YIN, Y. X., ZHANG, Y. G., LI, H. J., ZHAO, Y., CAI, E. B., ZHU, H. Y.,LI, P. Y.& LIU, J. P.*2019. Triterpenoids from fruits ofSorbus pohuashanensisinhibit acetaminophen-induced acute liver injury in mice.Biomedicine & Pharmacotherapy,109,493-502.

19. ZHU, H. L., LIN, H. Q., TAN, J., WANG, C. Z., QANG, H., WU, F. L., DONG, Q. H., LIU, Y. H.,LI, P. Y.*& LIU, J. P.* 2019. UPLC-QTOF/MS-Based Nontargeted Metabolomic Analysis of Mountain- and Garden-Cultivated Ginseng of Different Ages in Northeast China.Molecules,24,1-24.

20. BIAN, X. B., LIU, X. F., LIU, J. P., ZHAO, Y., LI, H. J., ZHANG, L. X.*,LI, P. Y. & GAO, Y. G. 2019. Hepatoprotective effect of chiisanoside from Acanthopanax sessiliflorus against LPS/D-GalN-induced acute liver injury by inhibiting NF-B and activating Nrf2/HO-1 signaling pathways.Journal of the Science of Food and Agriculture,99, 3283-3290.

21. RAN, N., PANG, Z. Q., GUAN, X. W., WANG, G. Q., LIU, J. P.,LI, P. Y., ZHENG, J. T. & WANG, F.*2019. Therapeutic Effect and Mechanism Study ofRhodiola wallichianavar. cholaensis Injection to Acute Blood Stasis Using Metabolomics Based on UPLC-Q/TOF-MS.Evidence-Based Complementary and Alternative Medicine,2019,20.

22. CHEN, L. X., QI, Z., SHAO, Z. J., LI, S. S., QI, Y. L., GAO, K., LIU, S. X., LI, Z., SUN, Y. S.*&LI, P. Y.*2019. Study on Antidepressant Activity of Pseudo-Ginsenoside HQ on Depression-Like Behavior in Mice.Molecules,24,13.

23. BIAN, X. B., WANG, S. J., LIU, J. P., ZHAO, Y.*, LI, H. J., ZHANG, L. X.*&LI, P. Y.2019. Hepatoprotective effect of chiisanoside against acetaminophen-induced acute liver injury in mice.Natural Product Research,33,2704-2707.

24. ZHANG, Q. H., LI, X. Z., HAN, L.,LI, P. Y.& LU, D.*2018. Determination of Sophorabioside in Rat Plasma by UPLC-MS/MS and its Application to a Pharmacokinetic Study.Journal of Chromatographic Science,56,154-159.

25. BIAN, X. B., LIU, X. F., LIU, J. P., ZHAO, Y.*, LI, H. J., CAI, E. B.,LI, P. Y. & GAO, Y. G.*2018. Study on antidepressant activity of chiisanoside in mice.International Immunopharmacology,57, 33-42.

26. FU, T. H., WANG, S. J., LIU, J. P., CAI, E. B., LI, H. J.,LI, P. Y. & ZHAO, Y.*2018. Protective effects ofα-mangostin against acetaminophen-induced acute liver injury in mice.European journal of pharmacology,827, 173-180.

27. YIN, Y. X., LIU, X. F., LIU, J. P., CAI, E. B., ZHU, H. Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& ZHAO, Y.*2018. Beta-sitosterol and its derivatives repress lipopolysaccharide/D-galactosamine-induced acute hepatic injury by inhibiting the oxidation and inflammation in mice.Bioorganic & Medicinal Chemistry Letters,28,1525-1533.

28. WANG, W. D., WANG, S. J., LIU, J. P., CAI, E. B., ZHU, H. Y.*, HE, Z. M., GAO, Y. G.,LI, P. Y.& ZHAO, Y.*2018. Sesquiterpenoids from the root ofPanax Ginsengprotect CCl4-induced acute liver injury by anti-inflammatory and anti-oxidative capabilities in mice.Biomedicine & Pharmacotherapy,102, 412-419.

29. WANG, W. D., ZHANG, Y. G., LI, H. J., ZHAO, Y.*, CAI, E. B., ZHU, H. Y.,LI, P. Y. & LIU, J. P.*2018. Protective Effects of Sesquiterpenoids from the Root ofPanax ginsengon Fulminant Liver Injury Induced by Lipopolysaccharide/d‑Galactosamine.Journal of agricultural and food chemistry,66, 7758-7763.

30. WANG, Y. R., WANG, C. Z., LIN, H. Q., LIU, Y. H., LI, Y. M., ZHAO, Y.,LI, P. Y.& LIU, J. P.*2018. Discovery of the Potential Biomarkers for Discrimination betweenHedyotis diffusa andHedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis.Molecules,23, 1525-1549.

31. TAN, J., WANG, C. Z., ZHU, H. L., ZHOU, B. S., XIONG, L. X., WANG, F.,LI, P. Y.*& LIU, J. P.*2018. Comprehensive Metabolomics Analysis of Xueshuan Xinmaining Tablet in Blood Stasis Model Rats Using UPLC-Q/TOF-MS.Molecules,23,16.

32. YIN, Y. X., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& GAO, Y. G.*2018. The effect of beta-sitosterol and its derivatives on depression by the modification of 5-HT, DA and GABA-ergic systems in mice.Rsc Advances,8,671-680.

33. FU, T. H., LI, H. J., ZHAO, Y.*, CAI, E. B., ZHU, H. Y.,LI, P. Y.& LIU, J. P.* 2018. Hepatoprotective effect of alpha-mangostin against lipopolysaccharide/D-galactosamine-induced acute liver failure in mice.Biomedicine & Pharmacotherapy, 106,896-901.

34. QI, Z., LI, Z., LI, W., LIU, Y., WANG, C., LIN, H., LIU, J. P. &LI, P. Y.*2018. Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice.Molecules (Basel, Switzerland),23,3038.

35. WANG, W. D., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& GAO, Y. G.*2018. Sesquiterpenoids from the Root ofPanax ginsengAttenuates Lipopolysaccharide-lnduced Depressive-Like Behavior through the Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase B and Sirtuin Type 1/Nuclear Factor-kappa B Signaling Pathways.Journal of agricultural and food chemistry,66,265-271.

36. WANG, Z. Z., LIN, H. Q., ZHU, H. L., YANG, N., ZHOU, B. S., WANG, C. Z.,LI, P. Y.*& LIU, J. P.*2018. Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MSE.Molecules,23,15.

37. WANG, C. Z., ZHANG, N. Q., WANG, Z. Z., QI, Z., ZHENG, B. Z.,LI, P. Y.*& LIU, J. P.*2017. Rapid characterization of chemical constituents ofPlatycodon grandiflorumand its adulterantAdenophora strictaby UPLC-QTOF-MS/MS.J. Mass Spectrom,52,643-656.

38. ZHANG, N. Q., WANG, C. Z., WANG, Z. Z., LI, Z., SAI, J. Y., MENG, Y., WANG, F., LI, P. Y.*& LIU, J. P.*2017. Anti-myocardial ischaemic effect of pseudoginsenoside F11 by inhibiting expression of beta1-adrenoceptor in rats with coronary artery ligation.Journal of functional foods,36, 224-232.

39. WANG, C. Z., ZHANG, N. Q., WANG, Z. Z., QI, Z., ZHU, H. L., ZHENG, B. Z.,LI, P. Y.*& LIU, J. P.*2017. Nontargeted Metabolomic Analysis of Four Different Parts ofPlatycodon grandiflorumGrown in Northeast China.Molecules,22,16.

40. BIAN, X., ZHAO, Y.*, GUO, X., ZHANG, L., LI, P., FU, T., WANG, W., YIN, Y., CHEN, G. & LIU, J. P.*2017. Chiisanoside, a triterpenoid saponin, exhibits anti-tumor activity by promoting apoptosis and inhibiting angiogenesis.Rsc Advances,7,41640-41650.

41. XIONG, L. X., QI, Z., ZHENG, B. Z., LI, Z., WANG, F., LIU, J. P.*& LI, P. Y.*2017. Inhibitory Effect of Triterpenoids fromPanax ginsengon Coagulation Factor X.Molecules,22,649-655.

42. LIU, X. J., XING, H. C., GAO, W. J., YU, D., ZHAO, Y. M., SHI, X. J., ZHANG, K.,LI, P. Y., YU, J. A., XU, W., SHAN, H. L., ZHANG, K. Y., BAO, W. G., FU, X. Q., YANG, S. R.*& WANG, S. F.*2017. A functional variant in the OAS1 gene is associated with Sjogren's syndrome complicated with HBV infection.Scientific Reports,7,9.

43. TENG, S. Y., WANG, Y.,LI, P. Y., LIU, J. H., WEI, A. H., WANG, H. T., MENG, X. K., PAN, D. & ZHANG, X. M.*2017. Effects ofRtype andStype ginsenoside Rg3 on DNA methylation in human hepatocarcinoma cells.Molecular Medicine Reports,15,2029-2038.

44. LI, W., ZHANG, X. R., XIN, Y. F., XUAN, Y. X., LIU, J. P.,LI, P. Y. & ZHAO, Y. Q.*2016. Oral subchronic toxicity evaluation of a novel antitumor agent 25-methoxydammarane-3, 12, 20-triol fromPanax notoginsengin Sprague-Dawley rats.Regulatory Toxicology and Pharmacology,77, 240-251.

45. ZHAO, Q.,LI, P. Y., JIANG, J. & HU, P.*2016. Pharmacokinetics of Single Ascending Doses and Multiple Doses of 20(S)-Ginsenoside Rg3 in Chinese Healthy Volunteers.European Journal of Drug Metabolism and Pharmacokinetics, 41,845-853.

46. XIONG, L. X., XIE, J. S., SONG, C. X., LIU, J. P., ZHENG, J. T., LIU, C. G., ZHANG, X. T.,LI, P. Y.*& WANG, F.* 2015. The Activation of Nrf2 and Its Downstream Regulated Genes Mediates the Antioxidative Activities of Xueshuan Xinmaining Tablet in Human Umbilical Vein Endothelial Cells.Evidence-Based Complementary and Alternative Medicine.

47. ZHENG, Q., LI, Z., LIU, J. P., HAN, L., ZHANG, N. Q., ZHANG, H., CHEN, J. L. &LI, P. Y.*2016. Two new dammarane-type triterpene sapogenins from Chinese red ginseng.Natural Product Research,30,95-99.

48. HAN, L., LI, Z., ZHENG, Q., LIU, J. P. &LI, P. Y.*2016. A new triterpenoid compound from stems and leaves of American ginseng.Natural Product Research,30, 13-19.

49. ZHAO, T., LIU, J. P., DONG, A., XIAO, L. &LI, P. Y.*2015. Synthesis of functionalized CdTe/ZnS nanoparticles as probes for norfloxacin fluorescence detection.Chalcogenide Letters,12,677-682.

50. HAN, L., LIN, M. Y., ZHENG, Q., LIU, H. Y., LIU, H. Y., DONG, G., LIU, J. P.*&LI, P. Y.*2014. A new epimer of ocotillol from stems and leaves of American ginseng.Natural Product Research,28,935-939.

51. YAN, Z. W., LIU, J. P., LU, D., NARLAWAR, R., GROUNDWATER, P. &LI, P. Y.*2014. Two new ceramides from the fruit pulp ofAcanthopanax senticosus(Rupr. et Maxim) Harms.Natural Product Research,28,144-149.

52. LU, J., LI, G. Y., HUANG, J., ZHANG, C., ZHANG, L., ZHANG, K.,LI, P. Y., LIN, R. C. & WANG, J. H.*2014. Lathyrane-type diterpenoids from the seeds ofEuphorbia lathyris.Phytochemistry,104,79-88.

53. HUO, J., WANG, H., HU, P., LI, P., LIU, J. & JIANG, J.* 2013. Determination of pseudo-ginsenoside GQ in human plasma by high performance liquid chromatography-tandem mass spectrometry.Biomedical Chromatography,27,1701-1707.

54. QIU, N. N., HU, J., LIU, J. P., WANG, F. &LI, P. Y.*2013. Preparation and Cytotoxic Activities of Fatty Acid Derivatives of 20(S)-Protopanaxatriol. Letters in Drug Design & Discovery,10, 402-409.

55. LIU, J. P., TIAN, X., LIU, H. Y., ZHANG, Q. H., LU, D.,LI, P. Y.& ZHAO, C. F.* 2013. Two novel dammarane-type compounds from the leaves and stems ofPanax quinquefoliumL.Journal of Asian Natural Products Research,15, 974-978.

56. LIN, M. Y., GAO, H. M., LIU, J. P., HAN, L., ZHANG, Q. H. &LI, P. Y.*2013. UPLC-MS/MS determination and pharmacokinetic study of 26-OH-panaxadiol in rat plasma.Analytical methods,5,6656-6662.

57. GAO, H. M., LI, Z.,LI, P. Y., LIN, M. Y., HAN, L., WANG, F. & LIU, J. P.*2013. Determination of Pseudoginsengenin DQ in rat plasma by UPLC-MS/MS and application of the method in a pharmacokinetic study.Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences,933,1-7.

58. HUANG, J., HAN, H. Y., LI, G. Y., WANG, H. Y., ZHANG, C., ZHANG, K., TAN, Y.,LI, P. Y.*& WANG, J. H. 2013. Two new terpenoid benzoates with antitumor activity from the roots ofFerula dissecta.Journal of Asian Natural Products Research,15, 1100-1106.

59. XIE, S. A., LI, G. Y., HUANG, J.*, ZHENG, Y. X., WANG, H. Y., ZHANG, K., GAO, H. Y., TAN, Y., CHEN, W., CHEN, H.,LI, P. Y.& WANG, J. H. 2013. A new flavanol fromCynomorium songaricum.Journal of Asian Natural Products Research,15,413-416.

60. LU, D., LIU, J. P., ZHAO, W. J. &LI, P. Y.*2012. Chronic toxicity of ginsenoside Re on Sprague-Dawley rats.Journal of Ethnopharmacology,144, 656-663.

61. LU, D.,LI, P. Y.& LIU, J. P.*2012. Quinquenoside F6, a new triterpenoid saponin from the fruits ofPanax quinquefoliumL.Natural Product Research,26, 1395-1401.

62. LIU, J. P., LU, D., NICHOLSON, R. C., ZHAO, W. J.,LI, P. Y.& WANG, F.* 2012. Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: A 26-week intramuscular repeated administration study in rats.Food and Chemical Toxicology,50,3388-3396.

63. ZHAO, Y., LIU, J. P., LU, D.,LI, P. Y.*& ZHANG, L. X.*2012. Two new xanthones from the pericarp ofGarcinia mangostana.Natural Product Research,26,61-65.

64. LIU, J. P., WANG, F.,LI, P. Y.& LU, D.*2012. A new ocotillol-type triterpenoid saponin from red American ginseng.Natural Product Research,26, 731-735.

65. LIU, J. P., LU, D. &LI, P. Y.*2012. A novel hexanordammarane glycoside from the leaves and stems ofPanax quinquefoliumL.Natural Product Research,26, 744-748.

66. LIU, J. P., LU, D., NICHOLSON, R. C.,LI, P. Y.& WANG, F.*2011. Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: A 26-week intramuscular repeated administration study in Beagle dogs.Food and Chemical Toxicology,49,1718-1727.

67. LIU, J. P., LU, D. &LI, P. Y.*2011. Two new dammarane-type triterpene saponins from red American ginseng.Journal of Asian Natural Products Research,13,198-204.

68. LI, N.*, HUANG, Y., XIAO, W., LIU, J. P.*, LI, X. &LI, P. Y.2011. Synthesis and Cytotoxic Activities of New Fatty Acid Esters of 20(S)-Protopanaxadiol. Zeitschrift Fur Naturforschung Section C-a Journal of Biosciences,66,199-204.

69. ZHAO, Y., LIU, J. P., LU, D.,LI, P. Y.*& ZHANG, L. X.*2010. A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn.Natural Product Research,24, 1664-1670.

70. YAN, Z. W., LIU, J. P., LU, D., GROUNDWATER, P., HE, C. Y. &LI, P. Y.*2010. A new 3,4-seco-lupane-type triterpenoid from the pulp ofAcanthopanax senticosus(Rupr. et Maxim) Harms.Natural Product Research,24,1523-1527.

71. LU, D., LIU, J. P. &LI, P. Y.*2010. Dihydrophenanthrenes from the stems and leaves ofDioscorea nipponicaMakino.Natural Product Research,24,1253-1257.

72. LU, D., LIU, J. P., LI, H. J. & LI, P. Y.*2010. Phenanthrene derivatives from the stems and leaves ofDioscorea nipponicaMakino.Journal of Asian Natural Products Research,12,1-6.

73. YAN, Z. W., LIU, J. P., LU, D., XUE, J. F. &LI, P. Y.*2009. A new bile acid from the bile of Anser anser.Natural Product Research,23,1312-1315.

74. ZHAO, Y., LIU, J. P., LU, D. &LI, P. Y.*2007. A novel cycloartane triterpene glycoside from the seeds ofCassia sopheraL.Natural Product Research,21,494-499.

75. LIU, J. P., LU, D., ZHAO, Y.,LI, P. Y.*& LI, X. 2007. A new semisynthetic ocotillol-type saponin and resuscitation of haemorrhagic shock.Journal of Asian Natural Products Research,9,103-113.

Books:

1. TANG, H. Y., XU, S., G.,LI, P. Y.2020.Organic Chemistry, Beijing Industry Press.

2.LI, P. Y., LIU, J. P. 2020.Ginseng Nutritional Components and Functional Factors, Springer.

3.LI, P. Y., LIU, J. P., WANG, F., 2020.Xuemai Shuangzhi-Xueshuan Xinmaining Tablets Modern Research,People's Medical Publishing Press.

4.LI, P. Y., LIU, J. P., FENG H. 2019.Zhongtonghuazheng Capsules-Pharmacy, Pharmacodynamics and Clinical Research, Chemical Industry Press.

5.LI, P. Y., LIU, J. P. 2017.Ginseng Nutritional Ingredients and Functional Factors, Chemical Industry Press.

6.LI, P. Y., LIU, J. P., LU, D. 2012.Ginsenoside NMR Standard Atlas, Chemical Industry Press.

7. ZHANG, H.,LI, P. Y., FENG, J., LIU, J. P. 2010.Efficacy and Scientific Administration of Ginseng.Jilin Publishing Group Co., Ltd.

8. ZHANG, J. T.,LI, P. Y., LU D., LIU, J. P. 2008.Ginseng Crown Herbs-Research Progress in Ginseng Chemistry, Biological Activity and Pharmacokinetics. Chemical Industry Press.

9. ZHANG, J. T.,LI, P. Y., LU, D., LIU, J. P. 2006.The Chemistry, Metabolism and Biological Activities of Ginseng, Chemical Industry Press.

10.LI, P. Y., ZHAO, CH. F., LIU, J. P. 2006.Research Progress on the Chemical Composition and Biological Activity of Kiwi Fruit, Jilin Science and Technology Press.

Pantents for inventions:

1. WU, F. L.,LI, P. Y., LIU, J. P.,WANG, D. H., GUO, W. Y., LI,Y. J. 2019.HPLC fingerprint chromatogram detection method for capsules capable of relieving pain and removing blood stasis. CN108445125B.

2. XIONG, L. Z., WANG, F., ZHANG, C., LU, Y. J., WANG, G. Q., GUAN, X. W., CHEN, F., ZHENG, J. Q., WANG, T.,LI, P. Y.2015.Application of compound in preparation of medicine for treating chronic obstructive pulmonary disease. CN105147670A.

3. LI, P. Y., ZHENG, Q., LIU, J. P., ZHANG, N.Q., WANG, Z.Z., ZHU, H.L., CHEN, J.L., ZHANG, H.2015.(20S,25R)-dammar-20,25-epoxy- 3β,12β,26,24β-tetrol and extracting method and medical applications thereof. CN104761609A.

4. HAN, L.,LI, P. Y., LIU, J. P., LI, Z., ZHENG, Q. 2015.Dama-20S, 25S-epoxy-3β, 12β, 26-triol as well as extracting method and pharmaceutical application thereof.CN104693262A.

5. ZHENG. Q.,LI, P. Y.,ZHANG, Q. H. 2014.Novel macamide compounds as well as synthetic method and medical application of novel macamide compounds. CN103980146A.

6. LI, P. Y., QIU, N. N., LIU, W. J., YANG, Y. F. 2013.Functional ginseng, preparation method and application of ginseng for treating male sexual dysfunction. CN103271959A.

7. LI, P. Y., SU, H., LIU, H. Y., DONG, G., LI, Z., CHEN, J.,TIAN, X., ZHANG, Q. H., LIU,J. P.2013. Pseudoginsenoside R1 and extraction method thereof, and applications of pseudoginsenoside R1 drug. CN103193847A.

8. LI. P. Y., LIN, M. Y., HAN, L., ZHENG, Q., LI, Z., LIU, H. Y., WANG, C. Z., LIU, J. P. 2013.Pseudoginsenoside RT6 and extraction method thereof, and applications of pseudoginsenoside RT6 drug. CN103193848A.

9. LI, P. Y., LIU, J. P. 2013.Application of extract of American ginseng fruit. CN102988441A.

10. LI, P. Y., LU, D., WANG, P., LIU, C. G., WANG, S.P., JIN, X.Q.2012. Drug combination. CN102688231A.

11. HAO, X. H., REN, Y. Y., ZHANG, Q. H., LIN, M. Y., LIU, H. Y.,LI, P. Y., LU, D., LIU, J. P.Dammar-20S, 25R-epoxy-3β, 12β, 26-triol and extraction method and drug use thereof. CN102329360A.

12. Zhong, F. L., LI,P. Y., WANG, X. L. 2011.Rosa davurica total flavone extract, its extracting method and its medical use. CN102228539A.

13. LI, P. Y., LIU, J. P., REN, Y. Y., LIU, C. G., HU, J. H., DU, X. J.Preparation method of 24(R)-ocotillol DQ and pharmacal application thereof. CN102050860A.

14. ZHONG, F. L.,LI, P. Y., LIU, J. P., LU, D., ZHAO, Y., WANG, X. L. 2011.Transplanted wild ginseng ginsenoside B as well as extraction method and medical application thereof. CN102050864A.

15. LI, P. Y., LIU, J.P.,TIAN, X., LIU, C.G., ZHU, J.Z., LI, F.2011.Method for extracting pseudoginsenoside RT5 and medical application. CN102010456A.

16. LI, P. Y., LIU, J.P., LIU, C. G., JIN, L.Q., ZHANG, G.M., YAN, Z.L., CHI, X.J. 2011.Application of pseudo-ginsenoside GQ. CN102008498A.

17. LI, P. Y., LU, D., WANG, P., LIU, C. G., WANG, S. P., JIN, L. Q.Girald daphne bark leaf extract and medicinal application thereof. CN102008599A.

18. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.20(R)-pseudoginsenoside F11 as well as extraction method and medical purpose thereof. CN101967170A.

19. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.Ginsenoside R10, extraction method and pharmaceutical use thereof. CN101948497A.

20. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.Pseudo-ginsenoside G2, extraction method and drug application thereof. CN101948498A.

21. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.Pseudoginsenoside G1 and extraction method and medicinal applications thereof. CN101948499A.

22. LIU, J. P.,LI, P. Y., LU, D., LI, Y. J. 2010.American ginseng ginsenoside F5ab and extraction method and medicinal application thereof. CN101928320A.

23. LI, P. Y., LIU, J. P., LU, D.,2010.Application of gartanin compound in preparing medicaments for treating hyperlipidemia. CN101869559A.

24. LU, D.,LI, P. Y., LIU, J. P. 2010.American ginseng saponin F6 as well as extraction method and medical application thereof. CN101863945A.

25. LI, P. Y., LIU,C. G., JIN, L. Q., WANG, F. W., WANG, W. J., YAN, Z. L., ZHANG, G. M. 2010.Goose gall extract, preparation method and medicine use thereof. CN101810643A.

26. ZHAO, W. J., NI, J. S.,LI, P. Y.2010.Application of 20(S)-ginsenoside Rg3 in preparation of medicines for treating non-small cell lung cancer. CN101732332A.

27. LIU, J. P.,LI, P. Y., LU. D., XUE. J. F. 2009.Hazel endothelin and extracting method and drug application thereof. CN101613340.

28. LI, P. Y., LU. D., LIU, J. P. 2009.Medicine composition for regulating blood fat. CN101584685.

29. LI, P. Y., LIU, J. P., LU, D., ZHOU, M. J. 2009.Application of acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia. CN101584719.

30. LIU, J. P.,LI, P. Y., LU, D., XUE, J. F. 2009.Hazelnut element B, extracting method and pharmaceutical use thereof. CN101550125.

31. LU, D.,LI, P. Y., LIU, J. P., LI, H. J. 2009.5-methylol-furfural-5-furfural-methanol, preparation method thereof and medical application thereof. CN101544624.

32. LU, D.,LI, P. Y., LIU, J. P., LI, H. J. 2009.Dimer (5-methylol-furfural), synthetic method thereof and medical application thereof. CN101544654.

33. LI, P. Y., LIU, J. P., LU, D., DU, X. J. 2009.Medical application of psuedo-ginsenoside F11. CN101524358.

34. LI, P. Y., LIU, J. P. 2009.Semi-synthetic method of pseudo-ginsenoside F11. CN101519419.

35. ZHAO, W. J., YAN, W. Q.,LI, P. Y., ZHANG, J. T. 2009.Use of bilobalide B in preparing medicine for promoting nerve cell regenerate. CN101396355.

36. LI, P. Y., LU, D., LU, A. P., LIU, J. P., DU, X. J. 2008.Simulated moving bed chromatography separation of 20(S) and 20(R)-ginsenoside Rg3 enantiomer.CN101230080.

37. LI, P. Y., LIU, J. P. 2005.Pseudoginsenoside Pdq and its semi-synthesis process and medicine use. CN1706862.

38. LI, P. Y., ZHAO, W. J., LIU, J. P. 2004.Herminium's triochistisaponine extract and its extraction refining method and its medical use.CN1537863.

39. ZHANG, J. T.,LI, P. Y., ZHAO, W. J. 2004.Application of ginsenoside Re for preparing medicine for curing dysmnesia.CN1498621.

40. LI, P. Y., LIU, J. P., LU, D. 2004.Extract of american ginseng fruit saponin, extracting and refining method and medicinal use thereof.CN1482136.

41. LI, P. Y., LI, P. 2003.Use of total polygalin in preparing medicine for promoting gastrointestinal peristalsis.CN1425384.

42. LI, P. Y., ZHAO, W. J., WU, J. X. 2000.Semisynthesizing method for 20(S)-ginsenoside Rg3, and use in medicine.CN1243128.

43. LI, P. Y., ZHAO, W. J. 2000.Process for extracting ginsenoside Re, and use of medicine thereof.CN1242374.

Copyright: School of Pharmacy

Baidu
sogou