LIU Jihua

author: Time:2023-04-04 Number of hits:

Name

Jihua Liu

Title

Professor, Doctoral supervisor


Address

Room 609, School of Pharmacitical Science

Tel.

0431-85619286

Email

liujh@jlu.edu.cn

Education Background

1990-1994 Bachlor, Traditional Chinese MeTraditional Chinese Medicine Pharmacy, College of Traditional Chinese Medicine, China Pharmaceutical University

2000-2003 Master, Medicinal Chemistry, School of Pharmacitical Science, Jilin University

2003-2008 Ph.D. , Biochemistry and Molecular Biology, College of Life Sciences, Jilin University

Work Experience

2017- Professor & doctoral supervisor, School of Pharmacitical Science, Jilin University

2010-2017, Vice Professor & master supervisor, School of Pharmacitical Science, Jilin University

2004-2010,Lecturer, School of Pharmacitical Science, Jilin University

Courses

Natural Product Chemistry;Spectroscopy Analysis of Organic Compounds

Research Field

Anticancer Drug; Research of Traditional Chinese Medicine;Drug Discovery;Pharmacokinetics Research

Scientific Research Achievements

1.Jia Wang, Hongliu Xie, Qinghai Dong, Jiayin Liu, Jun Su, Yang An, Baohua Zeng, Bingxue Sun, Jihua Liu*. The effect of arginine on inhibiting amyloid fibril derived from β-casein and the binding studies with multi-spectroscopic techniques[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.

2.Jihua Liu, Jia Wang, Wenhui Xu, Lei Zeng, Chunyu Wang, Yang An, Huimin Tian, Baohua Zeng, Qinghai Dong, Ye Ji, Xiaojun Gao, Guangguang Du, Jiayin Liu, Jun Su, Hongliu Xie, Lin Xie*. Amyloid fibril formation by casein and fatty acid composition in breast milk of mastitis patients[J]. J Food Biochem. 2022;46:e14183.

3.Qinghai Dong , Yang An , Guangguang Du , Jia Wang , Jiayin Liu , Jun Su , Hongliu Xie , Chongyang Liang , Jihua Liu*. Identification of ginsenoside metabolites in plasma related to different bioactivities of Panax notoginseng and Panax Ginseng[J]. Biomed Chromatogr. 2022 Jan 19;e5334.

4.Jihua Liu, Qinghai Dong, Guangguang Du, Jia Wang, Yang An, Jiayin Liu, Jun Su, Hongliu Xie, Jianyuan Yin. Identification of metabolites in plasma related to different biological activities of Panax ginseng and American ginseng[J]. Rapid Commun Mass Spectrom. 2022, 36(4),e9219.

5.Jia Wang, Jihua Liu*, Guangguang Du, Yang An, Chunfang Zhao and Baohua Zeng. The Influence of Ca2+ and Zn2+ on the Amyloid Fibril Formation by β-Casein[J]. Protein & Peptide Letters, 2020, 27, 1-9

6.Jihua Liu, Huizhu Gan, Ting Li, Jia Wang, Guangguang Du, Yang An, Xiaojing Yan, Cong Geng. The metabolites and biotransformation pathways in vivo after oral administration of ocotillol, RT5, and PF11[J]. Biomedical Chromatography. 2020;34:e4856.

7.Jihua Liu, Ting Li, Jia Wang, Chunfang Zhao, Cong Geng, Qin Meng, Guangguang Du, Jianyuan Yin. Different absorption and metabolism of ginsenosides after the administration of total ginsenosides and decoction of Panax ginseng[J]. Rapid Commun Mass Spectrom. 2020;34:e8788.

8.Jia Wang, He Zhu, Huizhu Gan, Qin Meng, Guangguang Du, Yang An, Jihua Liu*. The effect of heparan sulfate on promoting amyloid fibril formation by β-casein and their binding research with multi-spectroscopic approaches[J]. Journal of Photochemistry & Photobiology, B: Biology, 2020,202,111671

9.Liqun Zhang, Jia Wang, Ting Li, Pingya Li, Yunhua Wang, Miao Yang, Jinping Liu, Jihua Liu*. Determination of the chemical components and phospholipids of velvet antler using UPLC/QTOF‑MS coupled with UNIFI software[J]. Experimental and Therapeutic Medicine, 2019, 17(5): 3789-3799.

10.Xiuhua Hao, Ting Li, Lingjun Zhao, Yunhua Wang, Miao Yang, Jianyuan Yin, Jihua Liu*. Chemical ingredients identified from the white sap of Metaplexis japonica using UPLC-QTOF/MS[J]. Chemistry of Natural Compounds, 2019, 55(1): 164-168.

11.Fanbo Chen, Jianyuan Yin, Qin Meng, Fengquan Bu, Dandan Sun, Miao Yang, Yunhua Wang, Jihua Liu*. Interaction of the ginsenosides with κ-casein and their effects on amyloid fibril formation by the protein: Multi-spectroscopic approaches[J]. Journal of Photochemistry and Photobiology B: Biology.

12.Jihua Liu, Francis C. Dehle, Yanqin Liu, Elmira Bahraminejad, Heath Ecroyd, David C. Thorn, John A. Carver*. The effect of milk constituents and crowding agents on amyloid fibril formation by κ‑casein. [J] J. Agric. Food Chem, 2016, 64 (6): 1335–1343

13.Cong Geng, Jianyuan Yin, Xiuhua Yu, Yuxia Yang, Jingyan Liu, Dandan Sun, Fanbo Chen, Zhonglin Wei, Qin Meng,Jihua Liu*. Structural identification of neopanaxadiol metabolites in rats by ultraperformance liquid chromatography/ quadrupole-time-of-flight mass spectrometry[J]. Rapid Commun. Mass Spectrom. 2015, 29, 283–294.

14.Cong Geng, Jianyuan Yin, Xiuhua Yua, Jingyan Liu, Yuxia Yang,Deya Sun, Qin Meng, Zhonglin Wei and Jihua Liu*. Tissue distribution and excretion study ofneopanaxadiol in rats by ultra-performance liquid chromatography quadrupole time-offlight mass spectrometry[J]. Biomed. Chromatogr. 2015, 29: 333–340.

15.Fanbo Chen, Jianyuan Yin, Yunhua Wang, Miao yang, Qin Meng, Baohua Zeng, Dandan Sun, Jihua Liu*. Interaction of L-arginine with κ-casein and its effect on amyloid fibril formation by the protein: Multi-spectroscopic approaches[J]. Journal of Photochemistry and Photobiology B: Biology. 2015,143,130–138.

16.Jihua Liu, Fanbo Chen, Jianyuan Yin, Fengquan Bu, Baohua Zheng, Miao Yang, Yunhua Wang, Dandan Sun, Qin Meng. The effects of ginsenosides to amyloid fibril formation by RCMk-casein[J]. International Journal of Biological Macromolecules. 2015, 79, 49–55.

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