Zhou Xiaoping

author: Time:2023-04-04 Number of hits:

Name

Zhou Xiaoping

Title

Vice professor, Doctoral supervisor


Address

Room 604, School of Pharmactical Science

Tel.

0431-85619660

Email

zhouxp@jlu.edu.cn


Education Background

1991-1995 Bachelor, department of chemistry , Northeast Normal University

1998-2001 Master, Medicinal Chemistry, School of Pharmaceutical Science, Jilin University

2001-2005 Ph.D, Biochemistry and Molecular Biology, School of Pharmaceutical Science, Jilin University

Work Experience

2020-, Vice Professor&Ph.D.supervisor, School of Pharmaceutical, Jilin University;

2009-2019, Vice Professor&master supervisor, School of Pharmaceutical, Jilin University;

2006-2008, doctor (Ph.D), Graduate School of Medicine,Akita University, Japan

2002-2009, Lecturer, School of Pharmaceutical, Jilin University;

2001-2002,teaching assistant,School of Basic Medicine, Jilin University;

1995-1998,teaching assistant,School of Basic Medicine,Norman Bethune Medical University

Courses

Medicinal Chemistry 1;Clinical Medicinal Chemistry;Medicinal Chemistry

Research Field

Synthesis and structure-activity relationship of bioactive small molecules;Drug Discovery

Scientific Research Achievements

1.Xing, Cheng; Zhou, Xiaoping; Chen, Chengjuan; Sun, Wei; Zheng, Qingchuan; Liang, Di ; Stu

dies of Interaction Mechanism between Pyrido [3,4-d] Pyrimidine Inhibitors and Mps1, Molecules, 2021, 26(16): 0-5075

2.Yifan Chen, Xiaoping Zhou*.Research progress of mTOR inhibitors[J]. European Journal of Medicinal Chemistry,2020,208:112820

3.Kai Jiang, Xinlin Yan, Jiahao Yu, Zijian Xiao ,Hao Wu , Meihua Zhao,Yuandong Yue , Xiaoping Zhou*, Junhai Xiao*, Feng Lin a*.Design, synthesis, and biological evaluation of 3-amino-2- oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1[J]. European Journal of Medicinal Chemistry,2020,194:112252

4.Shutao Wang, Muxin Zhang, Di Liang, Wei Sun, Chaozai Zhang, Mengnan Jiang, Junli Liu,Jiaguo Li, Chenchen Li, Xiaohong Yang, Xiaoping Zhou*,Molecular design and anticancer activities of small-molecule monopolar spindle 1 inhibitors: A Medicinal chemistry perspective,European Journal of Medicinal Chemistry,2019, 175:247-268

5.Guiying Li, Yueyao Jiang, Yingjun Li, Tong He, Ying Wang, Tianyi Ji, Wanchen Zhai, Lichun Zhao*, Xiaoping Zhou*.Analysis and Biological Evaluation of Arisaema Amuremse Maxim Essential Oil[J]. Open Chem., 2019; 17(1): 647–654

6.Meng-Nan Jiang , Xiao-Ping Zhou , Dong-Ru Sun , Huan Gao , Qing-Chuan Zheng, Hong-Xing Zhang and Di Liang*. 2D-QSAR study, molecular docking, and molecular dynamics simulation studies of interaction mechanism between inhibitors and transforming growth factor-beta receptor I (ALK5)[J].Journal of Biomolecular Structure and Dynamics, ,2018,36(14):3705-3717

7.shen J, Li X, Zhang Z, Luo J, Long H, Tu Z, Zhou X*, Ding K*, Lu X*. 3-amino- pyrazolopyrazine derivatives as spleen tyrosine kinase inhibitors[J]. Chem Biol Drug Des,2016,88(5):690-698

8.Cao FY, Zhou XP*, Su J, Yang XH, Mu FH, Shen JY, Sun W..Chemical Structure Characteristics and Bioactivity of Small Molecule FAK Inhibitors[J].anti-cancer agents in medicinal chemistry, 2016, 16 (8):934-941

9.Zhou X, Koizumi Y, Zhang M, Natsui M, Koyota , Yamada , Kondo , Hamada , Sugiyama .. Cadmium-coordinated supramolecule suppresses tumor growth of T-cell leukemia in mice[J],Cancer Sci.,2015,106(5):635-41

10.Xiaoping Zhou, Muxin Zhang,Wei Sun,guangshu Wang, xiaohong Yang, dayuan sui, xiaofeng Yu, shaochun Qu. Design, Synthesis, and In-Vivo Evaluation of 4, 5-Diaryloxazole as Novel Nonsteroidal Anti- Inflammatory Drug, Biological & Pharmaceutical Bulletin, 2009, 32(12): 1986-1990

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