Address

Room 404, School of Pharmacitical Science

Tel.

17808075327

Email

weidongzhang@jlu.edu.cn

Education Background

1999-2003 Bachlor, Pharmaceutical Sciences, School of Pharmacitical Science, Jiamusi University

2003-2006 Master, Medicinal Chemistry, School of Pharmacitical Science, Jilin University

2006-2009 Ph.D. , Traditional Chinese Medicine， School of Pharmacitical Science, Chinese Pharmaceutical University

Work Experience

2018- Professor & doctoral supervisor, School of Pharmacitical Science, Jilin University

2017-2018 Associate Professor & master supervisor, School of Pharmacitical Science, Jilin University

2013-2017，Postdoctor, School of Pharmacitical Science, Memorial University of Canada

2012-2013 Postdoctor, School of Pharmacitical Science, National University of Singapore

Courses

Pharmaceutical analysis;Pharmacognosy

Research Field

Quality control for TCM;Biomarker identification; Natural Product.

Scientific Research Achievements

Publications:

1.Zhang WD, Sun S, Aitken D, Likhodii S,et al. Lysophosphatidylcholines to phosphatidylcholines ratio predicts advanced knee osteoarthritis. Rheumatology (Oxford), 2016;55:1566-74.

2.Zhang WD, Sun G, Likhodii S, et al. Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients. Osteoarthritis and Cartilage. 2016;24:827-34.

3.Zhang WD, Sun G, Likhodii S, Aref-Eshghi E, et al. Metabolomic analysis of human synovial fluid and plasma reveals that phosphatidylcholine metabolism is associated with both osteoarthritis and diabetes. Metabolomics. 2016,12:4.

4.Zhang WD, Likhodii S, Aref-Eshghi E, et al. Relationship Between Blood Plasma and Synovial Fluid Metabolite Concentrations in Patients with Osteoarthritis. J Rheumatol. 2015;42:859-65.

5.Zhang WD, Randell EW, Sun G,et al. Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes. PLoS One. 2017; 12;12(9):e**.

6.Zhang WD, Likhodii S, Zhang Y, et al. Classification of osteoarthritis phenotypes by metabolomics analysis. BMJ Open. 2014; 4(11):e006286.

7.Zhang WD, Wang PY, Wang Y, et al. Simultaneous determination of aurantio-obtusin, chrysoobtusin, obtusin and 1-desmethylobtusin in rat plasma by UHPLC-MS/MS. Biomed Chromatogr.2014, 28:369-74

8.Zhang WD, Wang Y, Wang Q,etal. Quality evaluation of Semen Cassiae by using ultra high-performance liquid chromatography coupled with mass spectrometry. Journal of Separation Science. 2012; 35, 2054-2062.

9.Zhang WD, Wang Q, Wang Y, etal. Application of ultrahigh-performance LC coupled with MS for analysis of lignans and quality control of Fructus Schisandrae chinensis. JSS. 2012;35, 2203-09.

10.Zhang WD, Yang WJ, Wang XJ. Simultaneous determination of tectorigenin, irigenin and irisflorentinin rat plasma and urine by UHPLC-MS/MS: Application to pharmacokinetics. J ChromatogrB. 2011; 879, 3735-3741.

11.Zhang WD, Wang XJ, Zhou SY, et al. Determination of free and glucuronidated kaempferol in rat plasma by LC-MS/MS : Application to pharmacokinetic study. J ChromatogrB.2010; 878, 2137-214.

12.Zhang WD, Qi LW, Yang XL, et al. Identification of the major metabolites of tectorigenin in rat bile by liquid chromatography combined with TOF and ion trap tandem mass spectrometry. RCM.2008; 22, 2677-84.

13.Zhang WD, Yang XL, Xu L. Identification of the key metabolites of tectorigenin in rat urine by LC-MSn. Biomed Chromatogr. 2009; 23, 219-221.

14.Zhang WD, Qi LW, Yang XL. Determination of tectorigenin in rat plasma:Application to a pharmacokinetic study after oral administration of tectorigenin or its prodrug tectoridin. Chromatogr.2008；68，1021-1025.

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